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Treatment Options For People With Lung Cancer

Several lung cancer treatments are currently available and the determination as to which one is prescribed depends on the lung cancer stage that has been diagnosed, the location of the cancer, and the patient’s health. The most common treatments for lung cancer include Surgery, Radiation, Chemotherapy, and Targeted Therapy.

In some cases you may choose not to undergo treatment. For instance, you may feel that the side effects of treatment will outweigh the potential benefits. When that’s the case, your doctor may suggest comfort (palliative) care to treat only the symptoms the cancer is causing, such as pain.

Treatment options for non-small cell lung cancers
Stage Common options
I Surgery
II Surgery, chemotherapy, radiation
IIIA Combined chemotherapy and radiation, sometimes surgery based on results of treatment
IIIB Chemotherapy, sometimes radiation
IV Chemotherapy, targeted drug therapy, clinical trials, supportive care
Treatment options for small cell lung cancers
Stage Common options
Limited Combined chemotherapy and radiation, sometimes surgery
Extensive Chemotherapy, clinical trials, supportive care

Surgery

Surgery involves cutting away a cancerous tumor and a portion of the tissue that has surrounded the tumor. Sometimes the surgical treatment involves removal of the entire affected lung. Surgery is often effective, but recovery time can be long. Because the surgeon will have to cut through the rib cage to get to the lungs, there will be pain and bed rest for one to two months after the procedure.

In addition to traditional surgical methods, other types of surgical procedures can be used depending on the location of the tumor and also the patient’s physical condition. A craniotomy, which is basically surgery performed through a hole made to the skull can be prescribed to tumors located in the brain.

Procedures to cutting or remove lung cancer include:

  • Wedge resection to remove a small section of lung that contains the tumor along with a margin of healthy tissue
  • Lobectomy to remove the entire lobe of one lung
  • Pneumonectomy to remove an entire lung

If you undergo surgery, your surgeon may also remove lymph nodes from your chest in order to check them for signs of cancer. If your lymph nodes contain cancer cells, this usually indicates that cancer has spread, even if cancer hasn’t been detected outside of your chest.

Lung cancer surgery carries risks, including bleeding and infection. Expect to feel short of breath after lung surgery. Your lung tissue will expand over time and make it easier to breathe. You may also feel pain in the muscles of your chest and in your arm on the side where you had the operation. Your doctor may recommend physical therapy or a rehabilitation program to help you restore your strength and range of motion.

Chemotherapy
Chemotherapy uses drugs to kill cancer cells. One or more chemotherapy drugs may be administered through a vein in your arm (intravenously) or taken orally. A combination of drugs usually is given in a series of treatments over a period of weeks or months, with breaks in between so that your body can recover.

Chemotherapy can be used as a first line treatment for lung cancer or as additional treatment after surgery. One problem associated with chemotherapy is that it can also cause damage to healthy cells and the cells that produce blood that reside within the bone marrow. Low blood counts can lead to a number of different problems so Chemotherapy treatment must be closely monitored.

Radiation therapy
Radiation therapy uses high-powered energy beams, such as X-rays, to kill cancer cells. Radiation therapy can be directed at your lung cancer from outside your body (external beam radiation) or it can be put inside needles, seeds or catheters and placed inside your body near the cancer (brachytherapy).

Radiation therapy can be used alone or along with other lung cancer treatments. Sometimes it’s administered at the same time as chemotherapy. Radiation therapy can also be used to lessen side effects of lung cancer.

Targeted drug therapy
Targeted therapies are newer cancer treatments that work by targeting specific abnormalities in cancer cells. Targeted therapy options for treating lung cancer include:

  • Bevacizumab (Avastin). Bevacizumab stops a tumor from creating a new blood supply. Blood vessels that connect to tumors can supply oxygen and nutrients to the tumor, allowing it to grow. Bevacizumab is usually used in combination with chemotherapy and is approved for advanced and recurrent non-small cell lung cancer. Bevacizumab carries a risk of severe bleeding.
  • Erlotinib (Tarceva). Erlotinib blocks chemicals that signal the cancer cells to grow and divide. Erlotinib is approved for people with advanced and recurrent non-small cell lung cancer that haven’t been helped by chemotherapy. Erlotinib side effects include a skin rash and diarrhea.

Clinical trials
Clinical trials are studies of new lung cancer treatment methods. You may be interested in enrolling in a clinical trial if lung cancer treatments aren’t working or if your treatment options are limited. The treatments studied in a clinical trial may be the latest innovations, but they don’t guarantee a cure. Carefully weigh your treatment options with your doctor. Your participation in a clinical trial may help doctors better understand how to treat lung cancer in the future.

Supportive (palliative) care
When treatments offer little chance for a cure, your doctor may recommend you avoid harsh treatments and opt for supportive care instead. If you’re receiving supportive care, your doctor may treat any signs and symptoms you experience to make you feel more comfortable, but you won’t receive treatment aimed at stopping your cancer. Supportive care allows you to make the most of your final weeks or months without enduring treatment side effects that can negatively impact your quality of life.

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